Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors inside the central anxious technique, conolidine modulates alternate molecular targets. A Science Innovations review identified that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availa... https://knoxzumdt.tribunablog.com/conolidin-to-replace-traditional-painkillers-fundamentals-explained-53292240